ReSViNET
  • Home
  • News & Events
    • News
    • Conferences >
      • 5th Meeting 2019
      • 4th Meeting 2017
      • 3rd Meeting 2017
      • 2nd Expert Meeting
      • 1st Expert Meeting
    • Webinars
  • About RSV
    • parents
    • RSV in Adults
    • professionals
    • Publications
  • about us
    • The foundation
    • Board members
  • patient network
  • contact us
  • Support us
    • Webshop
    • Donate

News on RSV Vaccine Development: the MVA platform 

8/14/2014

0 Comments

 
The promise of a safe and effective RSV vaccine is more realistic than ever before. Although no vaccine has entered phase 3 randomized clinical trials, the pharmaceutical landscape suggests a number of good candidates have well progressed into clinical development.  On July 8th, the  PATH Vaccine Snapshot website has been updated (sites.path.org/vaccinedevelopment/respiratory-syncytial-virus-rsv/).

One of the RSV vaccines which has now entered clinical development is an Modified Vaccinia Virus Ankara (MVA)-based RSV vaccine. For over 15 years MVA-based RSV vaccines have been developed at preclinical stage, but never went beyond. For the first time, it has now been combined with an adenovirus RSV vaccine to induce strong protective immunity against RSV.

The potential and mechanisms of MVA-based vaccines is discussed by Altenburg. MVA is a strongly attenuated vaccinia strain which can encode viral proteins making MVA a suitable candidate vaccine technology. Because MVA does not replicate in primates it has a favorable safety profile. According to www.clinicaltrials.gov the adenovector-MVA RSV vaccine phase 1 trial should have primary outcome data by now.

*Modified Vaccinia Virus Ankara (MVA) as Production Platform for Vaccines against Influenza and Other Viral Respiratory Diseases
Download file
0 Comments

    CATEGORIES

    All
    ReSViNET Publications


    ARCHIVES

    November 2020
    October 2020
    September 2020
    August 2020
    July 2020
    June 2020
    May 2020
    March 2020
    January 2020
    December 2019
    November 2019
    October 2019
    August 2019
    July 2019
    June 2019
    May 2019
    April 2019
    March 2019
    February 2019
    January 2019
    December 2018
    November 2018
    October 2018
    September 2018
    August 2018
    July 2018
    April 2018
    December 2017
    May 2017
    March 2017
    February 2017
    September 2016
    June 2016
    March 2016
    November 2015
    October 2015
    September 2015
    June 2015
    May 2015
    April 2015
    March 2015
    January 2015
    December 2014
    November 2014
    October 2014
    September 2014
    August 2014
    July 2014
    June 2014


    RSS Feed

Note: All information on ReSViNET is for educational purposes only. For specific medical advice, diagnoses, and treatment, consult your doctor.

2019 ReSViNET. All rights reserved.
about us
disclosure
contact
  • Home
  • News & Events
    • News
    • Conferences >
      • 5th Meeting 2019
      • 4th Meeting 2017
      • 3rd Meeting 2017
      • 2nd Expert Meeting
      • 1st Expert Meeting
    • Webinars
  • About RSV
    • parents
    • RSV in Adults
    • professionals
    • Publications
  • about us
    • The foundation
    • Board members
  • patient network
  • contact us
  • Support us
    • Webshop
    • Donate